First-in-Man 4-Chamber Pressure–Volume Analysis During Transcatheter Aortic Valve Replacement for Bicuspid Aortic Valve Disease

M Sarraf, D Burkhoff, M Brener
J Am Coll Cardiol Case Rep 2021;3:77–81

This report constitutes a first-in-man description of pressure–volume analysis in all 4 cardiac chambers before and after transcatheter aortic valve replacement. Pressure–volume analysis demonstrated that the hemodynamic consequences of valve replacement are chamber-specific and influenced by all aspects of the procedure (i.e., rapid ventricular pacing), not just valve deployment. (Level of Difficulty: Advanced.) ()

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